タンパク質寿命が制御するシン・バイオロジー

AAA+ ATPase chaperone p97/VCPFAF2 governs basal pexophagy. Fumika Koyano, Koji Yamano, Tomoyuki Hoshina, Hidetaka Kosako, Yukio Fujiki, Keiji Tanaka, Noriyuki Matsuda

• Nat Commun . 2024 Oct 29;15(1):9347. doi: 10.1038/s41467-024-53558-x

TBK1 adaptor AZI2/NAP1 regulates NDP52-driven mitochondrial autophagy. Ryu Endo, Hiroki Kinefuchi, Momoha Sawada, Reika Kikuchi, Waka Kojima, Noriyuki Matsuda, Koji Yamano

• J Biol Chem . 2024 Sep 12;300(10):107775. doi: 10.1016/j.jbc.2024.107775

Fluctuation of lysosomal protein degradation in neural stem cells of the postnatal mouse brain. Zhang, H., Ishii, K., Shibata, T., Ishii, S., Hirao, M., Lu, Z., Takamura, R., Kitano, S., Miyachi, H., Kageyama, R., Itakura, E., and Taeko Kobayashi*

• Development (2024) 151 (4): dev202231

Optineurin provides a mitophagy contact site for TBK1 activation. Koji Yamano, Momoha Sawada, Reika Kikuchi, Kafu Nagataki, Waka Kojima, Ryu Endo, Hiroki Kinefuchi, Atsushi Sugihara, Tomoshige Fujino, Aiko Watanabe, Keiji Tanaka, Gosuke Hayashi, Hiroshi Murakami, and Noriyuki Matsuda

• https://doi.org/10.1038/s44318-024-00036-1